Computational Tools #

VIPerturb-specific scripts #

Pipeline for preprocessing of bulk GuEST-List guide libraries for analysis with MaGeCK
- Bulk_Guest_List_Analysis_Script.txt - Example Script
- guest_fw_barcode.fasta - Barcode Reference File
- guest_list_protospacer_reference.csv - GuEST-List MaGeCK Reference File
Custom scripts for analyzing barcode-guides counts data generated from VIPerturb-seq multimodal data
- barcode_guides_quant.ipynb -Sample Jupyter Notebook for generating counts matrices
- GuEST_List_FullReference.txt - Reference file with all barcode combinations

Package for analyses of multimodal single-cell data in R

A novel computational method for analysis of perturbation single-cell data sets