VIPerturb-seq #

A platform for routine genome-wide single-cell CRISPR screens #

We’re excited to introduce VIPerturb-seq, a technology that enables cost-effective, genome-wide pooled CRISPR screens with single-cell readout. We hope the resources available on this page help researchers use VIPerturb-seq to run their own screens.


📚 Preprint now available

Check out our preprint on bioRxiv!

Read the preprint
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🦠 GuEST-List CRISPRi now on Addgene!

Run VIPerturb-seq experiments with our genome-wide human CRISPRi libraries.

Visit Addgene Page
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🧪 Experimental Protocols

Explore protocols and other helpful resources for running VIPerturb-seq.

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sgRNA Library Structure

🧬 Library Structures and Sequences

Understand the custom primers used in VIPerturb-seq assays.

Get sequences
sgRNA Library Structure

💻 Computational Resources

Get started with analysis of VIPerturb-seq data.

Find resources
sgRNA Library Structure